Enlarged Prostate · University Urology, PC

Advanced BPH Treatments in Knoxville, TN

Modern, minimally invasive options for enlarged prostate — matched to your anatomy, your goals, and your life. No one-size-fits-all approach.

About BPH

What is Benign Prostatic Hyperplasia (BPH)?

Benign Prostatic Hyperplasia — commonly called an enlarged prostate — is a non-cancerous growth of the prostate gland that affects the majority of men over 50. As the prostate grows, it can compress the urethra and obstruct urine flow, causing a range of urinary symptoms that progressively impact quality of life.

BPH is not prostate cancer and does not increase your cancer risk. But left untreated, it can worsen over time and lead to more serious complications including urinary retention, bladder damage, and recurrent infection.

The good news: we now have more effective, less invasive options than ever before. Most procedures are outpatient, recovery is measured in days rather than weeks, and the right choice depends on your specific anatomy — not a protocol.

Common BPH Symptoms

  • Frequent urination, especially at night (nocturia)
  • Weak, slow, or interrupted urine stream
  • Straining or hesitancy to start urination
  • Urgency — sudden strong need to urinate
  • Leakage or dribbling after urination
  • Sensation of incomplete bladder emptying

When to Seek Treatment

  • Symptoms disrupting sleep or daily life
  • Recurrent urinary tract infections
  • Urinary retention (inability to void)
  • Bladder stones or kidney complications
  • Symptoms worsening despite medications

Treatment Options

Advanced BPH Treatments We Offer

We offer the full spectrum of modern BPH therapies — from quick in-office procedures to robotic surgery for the largest glands. The right treatment depends on your prostate size, anatomy, symptom severity, and personal priorities.

UroLift® System

Minimally Invasive · In-Office or Outpatient

Small permanent implants are placed to lift and hold enlarged prostate tissue away from the urethra, opening the channel without cutting, heating, or removing tissue. No general anesthesia required for most patients.

Preserves ejaculation Rapid recovery Small–Medium prostate

iTind™ Procedure

Temporary Device · Outpatient

A temporary nitinol device is placed in the prostatic urethra and left in position for 5–7 days, gradually reshaping the channel to relieve obstruction. The device is then removed in office — no permanent implant left behind.

No permanent implant Preserves ejaculation Small–Medium prostate

Prostatic Artery Embolization (PAE)

Interventional Radiology · No Incisions

PAE is performed by an interventional radiologist rather than a urologist. Tiny particles are injected through a small catheter to reduce blood flow to the prostate, causing it to shrink over several weeks. No incision, no general anesthesia, and ejaculatory function is typically preserved. We coordinate referrals for appropriate candidates.

No incision Preserves ejaculation Select candidates

Robotic Simple Prostatectomy

Robotic Surgery · For Very Large Glands

For men with very large prostates — typically greater than 80–100 grams — where other options are not appropriate or have failed, robotic simple prostatectomy removes the obstructing inner portion of the prostate. Performed using the da Vinci robotic system by our fellowship-trained surgeons, this procedure offers the most durable symptom relief for high-volume glands.

Very large prostate Durable, definitive relief

Medical Management

Alpha-Blockers · 5-ARIs · Combination Therapy

Not every patient needs a procedure. For mild to moderate symptoms without obstruction-related complications, medications remain a reasonable first step. We help you understand when medical therapy is appropriate, when it's no longer working, and what comes next — without over-treating or under-treating.

Mild–Moderate symptoms Non-invasive

Choosing a Procedure

Which BPH Treatment Is Right for You?

We tailor our recommendation to your prostate size, anatomy (median lobe presence, obstruction pattern), symptom severity, medication history, and personal priorities — including whether preserving ejaculatory function matters to you. Your evaluation will typically include PSA, urinalysis, uroflow measurement, post-void residual, and cystoscopy or imaging when indicated.

Treatment Setting Recovery Prostate Size Ejaculation
UroLift In-office / Outpatient Days Small–Medium Typically preserved
iTind Outpatient Days Small–Medium Usually preserved
Aquablation ★ Only in Region Hospital / Outpatient 1–2 weeks Medium–Large Varies by anatomy
PAE IR Suite Days–1 week Medium–Large Typically preserved
Robotic Simple Prostatectomy Hospital 2–4 weeks Very Large (>80–100g) Varies
Medical Management Outpatient / Office None Any Preserved

This table is a general guide. Individual candidacy depends on a complete evaluation. Scroll horizontally on mobile to view all columns.


Why University Urology

Knoxville's Most Comprehensive BPH Center

We offer more BPH treatment options than any other practice in East Tennessee — and the subspecialty experience to know which one is right for you.

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More Options, Better Matching

From in-office UroLift to robotic surgery, we offer the full spectrum. Patients aren't pushed toward the one or two options a practice happens to offer — we recommend based on your anatomy and goals.

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East Tennessee's Only Aquablation Program

Dr. Ryan Pickens is the only urologist in the region performing Aquablation — robotic, image-guided waterjet resection for medium to large prostates with precision not achievable by hand.

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Fellowship-Trained Surgeons

Our BPH specialists — Dr. Pickens and Dr. Riedinger — completed fellowship training in endourology and advanced stone and prostate procedures. All of our urologists are experienced in the full range of BPH management.

Our BPH specialists: Dr. Ryan Pickens and Dr. Eric C. Riedinger lead our advanced BPH program. All of our urologists evaluate and manage BPH and can guide you to the therapy that best fits your anatomy, lifestyle, and goals.

Frequently Asked Questions

Common Questions About BPH Treatment

Do I need surgery, or will medication work?
It depends on your symptoms, obstruction severity, and how you've responded to medication. Many men do well on alpha-blockers or 5-alpha reductase inhibitors for years. When medications stop working, symptoms worsen, or complications develop — urinary retention, repeated infections, bladder damage — a procedure becomes the better option. We'll help you understand exactly where you fall.
Will BPH treatment affect my sexual function?
It depends heavily on which procedure you choose. UroLift and iTind are specifically designed to preserve ejaculatory function. Aquablation has favorable ejaculatory outcomes compared to traditional TURP. Robotic simple prostatectomy carries higher rates of retrograde ejaculation. Erectile function is generally not affected by BPH surgery itself, though underlying vascular or nerve factors may be. We discuss this carefully at your consultation.
What is Aquablation and why isn't it available everywhere?
Aquablation uses a robotic arm guided by real-time transrectal ultrasound to deliver a precise waterjet that removes obstructing prostate tissue with a level of spatial accuracy that manual resection can't match. It requires specialized equipment and training, which is why it's only available at select centers. Dr. Pickens is the only physician performing Aquablation in East Tennessee.
How do I know what prostate size I have?
Prostate volume is measured by transrectal or transabdominal ultrasound, or estimated from MRI. Your evaluation at University Urology will include an assessment of prostate size — this is one of the most important factors in selecting the right procedure, particularly for Aquablation and robotic prostatectomy.
Does insurance cover these procedures?
Most major BPH procedures — UroLift, Aquablation, and robotic simple prostatectomy — are covered by Medicare and most commercial insurance plans when medically indicated. PAE coverage varies by carrier. iTind coverage is expanding. We verify coverage before scheduling any procedure and assist with prior authorization when required.
How do I get started?
Message us through Klara, call (865) 305-9254, or ask your primary care provider to send a referral. Most patients are seen within a few weeks, and many BPH evaluations can begin at any of our satellite locations across East Tennessee before determining whether an in-person procedure at UTMC is needed.

Ready to Find Relief?

Schedule a BPH consultation with our team. We'll evaluate your anatomy, review your history, and recommend the treatment that's right for you — not a protocol.